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Dosing ArithmeticVial yield and repeat-interval arithmetic, on figures you supply.

A half-life of 72 hours

Every figure on this page is a function of one number: 72 hours. Five of those is 15 days, and down to one percent takes about 478 hours. No compound is named here and none is implied.

Educational arithmetic only. Not medical advice and not a dosing protocol.

Whole multiples of a 72-hour half-life. The percentage column is exact: one half to the power n is a rational number and is computed as one, so these figures are not rounded decimals.
Half-lives elapsedRemaining, exactlyElapsedWhich is
150.0000%72 hours3 days
225.0000%144 hours6 days
312.5000%216 hours9 days
46.2500%288 hours12 days
53.1250%360 hours15 days
61.5625%432 hours18 days
70.7813%504 hours21 days
Clock time to five remaining fractions. These are approximate: the exponent is fractional except at whole multiples of the half-life, so the value is irrational and is rounded for display.
ToRemainingHours, aboutWhich is about
Down to a half50%72.0 hours3 days
Down to a quarter25%144.0 hours6 days
Down to a tenth10%239.2 hours9 days 23.2 hours
Down to a twentieth5.0%311.2 hours12 days 23.2 hours
Down to a hundredth1.0%478.4 hours19 days 22.4 hours
A 72-hour half-life against seven intervals. The interval is a parameter in this table and nothing more: no row is a suggestion, and the second column is the only thing that determines the rest of the row.
IntervalIntervals per half-lifeSurviving the gapLimit the peaks approachIntervals to within 1%
8 hours0.1192.6%13.49x60
12 hours0.1789.1%9.17x40
24 hours0.3379.4%4.85x20
48 hours0.6763.0%2.70x10
72 hours1.0050.0%2.00x7
168 hours2.3319.8%1.25x3
336 hours4.673.9%1.04x2

What is particular to this half-life

Three days, and the first value where a weekly interval does something interesting: 168 hours is about 2.3 half-lives, so a fifth of one amount survives the week and the limit is about 1.25. The daily column, by contrast, is up at about 4.8. The spread across one row of this table is the clearest illustration on the site that only the ratio matters.

Reading the third table

The second column is the whole story. It is the interval divided by the half-life, and it is the only input to the three columns after it: the fraction surviving a gap is 0.5 to that power, and the limit is one over one minus that fraction. Two rows with the same figure in column two have identical arithmetic however different the clock times are.

At a 72-hour half-life and a 24-hour interval, 0.33 half-lives pass between repeats, about 79.4% of one amount survives the gap, and the peaks approach about 4.85 times one amount after roughly 20 intervals. Every one of those four figures comes from the ratio and from nothing else.

Why the first table is exact and the other two are not

At whole multiples of a half-life the exponent is a whole number, so the remaining fraction is exactly one half to the power n - a rational number, computed as one. That is why the first table has figures like 3.1250% in it rather than 3.13%.

Everywhere else the exponent is fractional and the value is irrational. There is no exact decimal to print, so those tables are computed in floating point and labelled approximate. Exact and approximate sets out which figures across this whole site are which, and why the distinction is worth making rather than papering over.

What this page is not

It is not about a compound. No substance has a 72-hour half-life as far as this page is concerned; 72 hours is a number, chosen as one of ten points spanning the range this arithmetic is useful over. A published half-life belongs to the species, formulation, route and assay that measured it, and this site holds no such figure for anything.

It is also not a schedule. The intervals in the third table are parameters swept across a plausible range so that the shape of the function is visible. None of them is a proposal, and what this does not do is explicit about that.

Elsewhere on this site