Skip to the arithmetic
Dosing ArithmeticVial yield and repeat-interval arithmetic, on figures you supply.

Exact and approximate

This site does two kinds of arithmetic with two different guarantees, and mixing them up would be a way of overstating one of them. So every figure is labelled.

Educational arithmetic only. Not medical advice and not a dosing protocol.

The exact kind

Every quantity in the vial arithmetic is held as a fraction of two whole numbers and rounded once, at the point of display. Five milligrams in three millilitres is held as exactly five thirds of a milligram per millilitre, not as 1.6666666666666667, and a chain of four conversions cannot accumulate drift in the digit a reader acts on.

That covers the draw count, the remainder, the exact ratio, every strength, every volume, every unit reading, and the fractions at whole multiples of a half-life - because one half to the power of a whole number is rational. Those figures are not estimates and are not labelled as such.

The approximate kind

The fraction remaining at an arbitrary time is 0.5t ÷ t½, and for most inputs the exponent is fractional and the value is irrational. There is no exact decimal to print. The same applies to everything derived from it: the retained fraction across an interval, the accumulation limit, the number of intervals to approach it, and every point on a plotted curve.

Those are computed in double-precision floating point and every one of them is labelled about in the worksheets and approximate in the tables. The error is far below anything that matters at the precision these figures are quoted to; the label is there because the distinction is real, not because the numbers are shaky.

Which figures are which. The third column is what the label on the figure says, and it is generated from the same flag the engine sets rather than written by hand.
FigureKindHow it is labelled
Draws in a vial, and the remainderExactno qualifier
Strength from a measured finished volumeExactno qualifier
Strength from a mass and a diluent volumeExact, but a boundat most
Volume derived from a bounded strengthExact, but a boundat least
Unit reading on a barrelExactwith the nearest printed mark named
Fraction remaining at whole half-livesExactno qualifier
Fraction remaining at any other timeApproximateabout
Accumulation limit and intervals to settleApproximateabout

A bound is a third category and the most useful one

A strength computed from a mass and a diluent volume is exact arithmetic on the wrong denominator. The dissolved solid takes up room, so the finished solution is larger than the diluent and the true strength is lower than the figure. The calculation has no error in it; the premise does.

Which makes the honest label "at most" rather than "approximately". The figure is not uncertain in both directions - it is an upper bound, true for every possible displacement, and the volume derived from it is correspondingly a lower bound. Getting the direction of an uncertainty right is worth more than widening it symmetrically.

Why this distinction is worth a page

Because precision is persuasive. A figure printed to three decimal places reads as authoritative whether or not the quantity behind it deserves three decimals, and a site that prints both kinds in the same typeface with no label is borrowing credibility from the half it earned.

It also matters for checking. An exact figure can be reproduced by hand and must match to the last digit; an approximate one will not, and knowing which you are checking saves concluding there is a bug when there is only a rounding difference in the twelfth decimal place.