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Dosing ArithmeticVial yield and repeat-interval arithmetic, on figures you supply.

A half-life of 336 hours

Every figure on this page is a function of one number: 336 hours. Five of those is 70 days, and down to one percent takes about 2232 hours. No compound is named here and none is implied.

Educational arithmetic only. Not medical advice and not a dosing protocol.

Whole multiples of a 336-hour half-life. The percentage column is exact: one half to the power n is a rational number and is computed as one, so these figures are not rounded decimals.
Half-lives elapsedRemaining, exactlyElapsedWhich is
150.0000%336 hours14 days
225.0000%672 hours28 days
312.5000%1008 hours42 days
46.2500%1344 hours56 days
53.1250%1680 hours70 days
61.5625%2016 hours84 days
70.7813%2352 hours98 days
Clock time to five remaining fractions. These are approximate: the exponent is fractional except at whole multiples of the half-life, so the value is irrational and is rounded for display.
ToRemainingHours, aboutWhich is about
Down to a half50%336.0 hours14 days
Down to a quarter25%672.0 hours28 days
Down to a tenth10%1116.2 hours46 days 12.2 hours
Down to a twentieth5.0%1452.2 hours60 days 12.2 hours
Down to a hundredth1.0%2232.3 hours93 days 0.3 hours
A 336-hour half-life against seven intervals. The interval is a parameter in this table and nothing more: no row is a suggestion, and the second column is the only thing that determines the rest of the row.
IntervalIntervals per half-lifeSurviving the gapLimit the peaks approachIntervals to within 1%
8 hours0.0298.4%61.09x280
12 hours0.0497.6%40.90x187
24 hours0.0795.2%20.70x94
48 hours0.1490.6%10.61x47
72 hours0.2186.2%7.24x32
168 hours0.5070.7%3.41x14
336 hours1.0050.0%2.00x7

What is particular to this half-life

A fortnight, the longest value here. Five half-lives is seventy days. At every interval in the table the gap is a fraction of the half-life, so a large share survives each one and every limit is high. This is the regime where the number of intervals to approach the limit - thirty-three at a weekly interval - is the figure worth reading rather than the limit itself.

Reading the third table

The second column is the whole story. It is the interval divided by the half-life, and it is the only input to the three columns after it: the fraction surviving a gap is 0.5 to that power, and the limit is one over one minus that fraction. Two rows with the same figure in column two have identical arithmetic however different the clock times are.

At a 336-hour half-life and a 24-hour interval, 0.07 half-lives pass between repeats, about 95.2% of one amount survives the gap, and the peaks approach about 20.70 times one amount after roughly 94 intervals. Every one of those four figures comes from the ratio and from nothing else.

Why the first table is exact and the other two are not

At whole multiples of a half-life the exponent is a whole number, so the remaining fraction is exactly one half to the power n - a rational number, computed as one. That is why the first table has figures like 3.1250% in it rather than 3.13%.

Everywhere else the exponent is fractional and the value is irrational. There is no exact decimal to print, so those tables are computed in floating point and labelled approximate. Exact and approximate sets out which figures across this whole site are which, and why the distinction is worth making rather than papering over.

What this page is not

It is not about a compound. No substance has a 336-hour half-life as far as this page is concerned; 336 hours is a number, chosen as one of ten points spanning the range this arithmetic is useful over. A published half-life belongs to the species, formulation, route and assay that measured it, and this site holds no such figure for anything.

It is also not a schedule. The intervals in the third table are parameters swept across a plausible range so that the shape of the function is visible. None of them is a proposal, and what this does not do is explicit about that.

Elsewhere on this site